Search results for " State of the art"

showing 5 items of 5 documents

NOTCH signalling in ovarian cancer angiogenesis

2020

The Notch signalling pathway is involved in the new vessel formation process by regulating tip and stalk cells, which are key cells in the sprout formation. This process is essential in both normal ovary and cancer angiogenesis and is regulated by Notch-VEGF crosstalk. Furthermore, Notch has been linked in ovary with stem cell maintenance and epithelial mesenchymal transition processes. Dysregulation of the Notch pathway is frequent in ovarian cancer (OC) and it has been associated with impaired survival and advanced stages or lymph node involvement. Notch also plays a role in chemoresistance to platinum. In this context, this pathway has emerged as an attractive target for precision medici…

0301 basic medicineDemcizumabAngiogenesisNotch signaling pathway610 Medicine & healthContext (language use)General MedicineBiologymedicine.disease10174 Clinic for Gynecology03 medical and health sciencesReview Article on Ovarian Cancer: State of the Art and Perspectives of Clinical Research030104 developmental biology0302 clinical medicine030220 oncology & carcinogenesismedicineCancer researchEpithelial–mesenchymal transitionStem cellOvarian cancerGamma secretaseAnnals of Translational Medicine
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Progetti di lessicografia onomastica dell’Atlante Linguistico della Sicilia

2022

L’Atlante Linguistico della Sicilia ha adottato, già una decina di anni fa, lo strumento del dizionario-atlante. Quando si è cominciato ad indagare il ricco universo onomastico, se ne è valutata la spendibilità anche su tre diversi corpora orali: uno relativo alle forme popolari del patrimonio toponomastico (DAToS, Dizionario-atlante toponomastico della Sicilia), uno riguardante l’inventario plurale dei soprannomi etnici (DASES, Dizionario-atlante dei soprannomi etnici in Sicilia), l’ultimo afferente al patrimonio antroponomastico popolare, individuale e familiare (DASS, Dizionario-atlante dei soprannomi di/in Sicilia). Il contributo fornisce lo stato dell’arte dei tre progetti e ne descriv…

About ten years ago the Linguistic Atlas of Sicily (ALS) adopted the dictionary-atlas tool. When the rich onomastic universe began to be investigated its use was also evaluated on three different oral corpora: one relating to the popular forms of the toponymic heritage (DAToS Dictionary-toponymic atlas of Sicily) one concerning the plural inventory of ethnic nicknames (DASES Dictionary-atlas of ethnic nicknames in Sicily) the latest afferent to the popular individual and family anthroponomastic heritage (DASS Dictionary-atlas of the nicknames of / in Sicily). The contribution provides the state of the art of the three projects and describes their methods objectives and dissemination tools.Settore L-FIL-LET/12 - Linguistica Italiana
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Italian experiences in Life Cycle Assessment of olive oil: a survey and critical review

2010

Settore SECS-P/13 - Scienze MerceologicheLife Cycle Assessment Olive oil Italy State of the art Italian LCA Network
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Profetismo político, milenarismo y creencias mesiánicas en el último periodo del reinado de Fernando el Católico (1500-1516)

2019

This study analyzes the presence of messianic and millennial beliefs in the last period of Ferdinand the Catholic?s reign. For this and after a brief state of the art, we analyze the use of the Christian prophecy of the millennium in speeches and memorials arising from the war in Naples, the North African campaign and the Pisan schism.

UNESCO::HISTORIARevista de historia moderna 529735 2019 45 7107722 Profetismo político [0210-9093 553 Estudis]we analyze the use of the Christian prophecy of the millennium in speeches and memorials arising from the war in Naplesmessianismprofetismo políticoJuan Diego This study analyzes the presence of messianic and millennial beliefs in the last period of Ferdinand the Catholic?s reign. For this and after a brief state of the artthe North African campaign and the Pisan schism. Fernando el Católicomesianismo0210-9093 553 Estudis: Revista de historia moderna 529735 2019 45 7107722 Profetismo políticomillenarianismpolitical prophetism 331 343milenarismo:HISTORIA [UNESCO]Ferdinand the Catholicmilenarismo y creencias mesiánicas en el último periodo del reinado de Fernando el Católico (1500-1516) García González
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Il primo concorso per il Palazzo di Giustizia a Roma del 1884. Ricostruzione critica del progetto di Ernesto Basile

2019

1. Breve descrizione dell’oggetto di studio Il concorso del Palazzo di Giustizia di Roma si svolge in quattro fasi svolte tra il 1884 e il 1887. Il progetto per il primo concorso, del 1884, redatto dall’allora giovanissimo Ernesto Basile (Palermo 1857-1932), rivela una grande perizia progettuale che trasforma il complesso programma funzionale in un austero edificio in stile neofiorentino. I disegni originari dell’opera, non realizzata, conservati presso la Dotazione Basile del Dipartimento di Architettura dell’Università di Palermo, sono stati oggetto di studio propedeutico alle fasi di analisi, interpretazione e ricostruzione congetturale del modello digitale. 2. Stato dell’arte e riferime…

the spatiality of the great vestibule• elaboration of axonometric and perspective view• choice of interpretation criteria in case of project incongruitiethe vaulted arcades.the space of the main courtyard which Basile outlines in a sketch• elaboration of analytical drawings (modular functional compositional volumetric schemes)• modular study and flat vectorization• application of rendering techniques consistent with the available information. 4. Objectives pursued and achieved Conjectural reconstruction achieved the following results: • formulation of analytical documents which show how the planimetric and altimetric articulation are perfectly consistent with the functional program• definition of the level of uncertainty1. Brief description of the object of study The competition of the Palace of Justice in Rome takes place in four phases between 1884 and 1887. The project for the first competition in 1884 drawn up by the then very young Ernesto Basile (Palermo 1857-1932) reveals a great deal of design expertise that transforms the complex functional program into an austere building in neo-florentine style. The original drawings of the building not realized kept in the Basile Endowment of the Department of Architecture of the University of Palermo have been the subject of preliminary study to the phases of analysis interpretation and conceptual reconstruction of the digital model. 2. State of the art and main bibliographical references The conjectural reconstruction on the basis of drawings and archival documents is a well-established and codified practice thanks to various disciplinary contributions at national and international level. See: F. I. Apollonio Classification Schemes for Visualization of Uncertainty in Digital Hypothetical Reconstruction in M. Sander P. Mieke P. Kuroczyński M. Ioannides 3D Research Challenges in Cultural Heritage II Cham (CH) 2016. G. Antista M. Cannella Ricostruire. Architettura - Storia – Rappresentazione Palermo 2015. For studies related to the examinated project see: E. Mauro E. Sessa I disegni della Collezione Basile Roma 2015. E. Sessa Ernesto Basile. Dall'eclettismo Classicista al Modernismo Palermo 2002. 3. Definition of the methodologies adopted in the research Methodological phases: • historical analysi• survey of the original drawings and dimensional verification of the flat scanSettore ICAR/17 - Disegno• construction of perspective views deduced from the original drawings that highlight: the volumetric hierarchy and the function of the bugnate in the scanning of the masonry ma• three-dimensional modeling
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